Mammalian ORFs
ABclonal Technology PDE6D Rabbit pAb
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
ABclonal Technology p-LATS1-T1079-LATS2-T1041
The protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis The protein is phosphorylated in a cell-cycle dependent manner with late prophase phosphorylation remaining through metaphase The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative regulator of CDC2 cyclin A In addition the C-terminal kinase domain binds to its own N-terminal region suggesting potential negative regulation through interference with complex formation via intramolecular binding Biochemical and genetic data suggest a role as a tumor suppressor This is supported by studies in knockout mice showing development of soft-tissue sarcomas ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments
Biolegend PerCP/Cyanine5.5 anti-human CD
PerCP/Cyanine5.5 anti-human CD340 (erbB2/HER-2) [24D2]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
![Genetex Inc CD45 Monoclonal Antibody [MSVA-045R] HistoMAX™ (GTX04432) GeneTex - IHC-Optimized Antibody.](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3666940.jpg-250.jpg)
Genetex Inc CD45 Monoclonal Antibody [MSVA-045R] HistoMAX™ (GTX04432) GeneTex - IHC-Optimized Antibody.
The CD45 antibody [MSVA-045R] HistoMAX™ (GTX04432) is a Rabbit Monoclonal antibody in the GeneTex HistoMAX portfolio. The antibody is extensively evaluated for IHC-P using formalin-fixed human normal tissues (more than 70 different sections) and cancer tissue arrays to guarantee specificity and best-in-class performance. Information regarding both manual and autostainer staining protocols are available.Figure Legend: IHC-P analysis of human diffuse large B-cell lymphoma (DLBCL) from lymph node tissue using GTX04432 CD45 antibody [MSVA-045R] HistoMAX. Diffuse large B cell lymphoma showing strong CD45 staining of tumor cells.
HORIZON DISCOVERY BIOSCIENCES LIMITED ORFEOME COLLAB. MM GABBR2 ORF
NC2603667 ORFEOME COLLAB. MM GABBR2 ORF
Sino Biological Human, OR3A1 cDNA ORF Clone, N-HA tag
Full length Clone DNA of Human olfactory receptor, family 3, subfamily A, member 1 with N terminal HA tag.
Sino Biological Mouse, CD45 cDNA ORF Clone, untagged
Full length Clone DNA of Mouse protein tyrosine phosphatase, receptor type, C.